Symbol
Name
ID

Cd86
CD86 antigen
MGI:101773

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Abnormal bleeding	Chronic lymphatic leukemia	Thrombocytopenia
Disease(s) Associated with CD86	Abnormal bleeding	Chronic lymphatic leukemia	Thrombocytopenia
autoimmune thrombocytopenic purpura
chronic lymphocytic leukemia

Mouse Phenotypes

abnormal T cell proliferation

decreased T cell proliferation

spleen hyperplasia

abnormal B cell differentiation

decreased B cell number

decreased CD4-positive, alpha-beta T cell number

increased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased regulatory T cell number

increased T cell number

absent spleen germinal center

increased splenocyte number

decreased IgG level

abnormal CD4-positive, alpha-beta T cell physiology

Availability

Mouse Genotype

Cd86^tm1Shr/Cd86^tm1Shr

Tg(H2-K-Cd86)7All/0

Tg(H2-K-Cd86)27All/0

Tg(H2-K-Cd86)31All/0

Tg(Igh-6-Cd86)1Akab/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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